Correlation of Bis Index with Clinical Sedation Score During Mechanical Ventilation in Intensive Care Unit Patients

Background: Mechanical ventilation and sedation are inextricably linked components of critical care that represent, what we do for the patients during their vulnerable course in ICU. Aims: The aim of the present study is to evaluate the use of BIS for monitoring sedation in mechanically ventilated ICU patients and correlation of BIS with Sedation Agitation Scale. Settings and Design: Prospective Observational study. Methods and Material: In this study, recruited patients were allocated into two groups of 10 patients each. Group A(Non-surgical) and Group B (Surgical) patients received Inj. Propofol and Inj. Midazolam for sedation. Hemodynamic parameters, correlation of BIS with SAS, duration of mechanical ventilation and mortality were assessed in both groups. Statistical Analysis: Mean and standard deviation was calculated. We applied correlation technique that is Pearson Product-moment correlation coefficient (r) to assess correlation between BIS and SAS. It varies from +1 to 0 to -1. Results: In this study in non surgical group 8 patients shown moderate to strong correlation while in group B, 9 patients had shown moderate to strong correlation between BIS and sedation agitation scale Conclusion:. BIS monitor may be effectively used for prolonged periods in sedated, mechanically ventilated ICU patients and BIS correlates with clinical sedation scores.